药物治疗是缓解早泄的有效方法之一，但需要在医生指导下选择合适的药物。本文将介绍常用的早泄治疗药物及其使用注意事项。
Medication is one of the effective methods for relieving premature ejaculation, but it requires doctor’s guidance to choose the appropriate drugs. This article introduces commonly used PE treatment medications and their usage considerations.
1. 常用口服药物 / Common Oral Medications
选择性5-羟色胺再摄取抑制剂（SSRIs）
这类药物通过调节大脑中5-羟色胺水平来延迟射精：
- 达泊西汀：唯一专门用于早泄治疗的SSRI药物
- 优点：快速起效，按需服用
- 用法：性交前1-3小时服用
- 剂量：通常30mg或60mg
- 帕罗西汀：
- 优点：效果显著
- 缺点：需要每日服用
- 剂量：每日20-40mg
- 舍曲林：
- 优点：耐受性较好
- 用法：每日一次
- 剂量：50-100mg/天
Selective Serotonin Reuptake Inhibitors (SSRIs)
These drugs delay ejaculation by regulating serotonin levels in the brain:
- Dapoxetine: The only SSRI specifically for PE treatment
- Advantages: Fast-acting, taken as needed
- Usage: Taken 1-3 hours before intercourse
- Dosage: Usually 30mg or 60mg
- Paroxetine:
- Advantages: Significant effect
- Disadvantages: Requires daily intake
- Dosage: 20-40mg daily
- Sertraline:
- Advantages: Good tolerance
- Usage: Once daily
- Dosage: 50-100mg/day
2. 局部外用药物 / Topical Medications
局部麻醉剂
通过降低龟头敏感度来延长射精时间：
- 利多卡因喷雾/药膏：
- 用法：性交前20-30分钟涂抹
- 注意：使用后需清洗，避免影响伴侣
- 效果：快速起效，局部作用
- 普鲁卡因乳膏：
- 优点：作用时间可控
- 注意：可能影响勃起硬度
- 建议：与医生讨论适用性
Topical Anesthetics
Prolong ejaculation time by reducing glans sensitivity:
- Lidocaine spray/ointment:
- Usage: Applied 20-30 minutes before intercourse
- Note: Needs cleaning after use to avoid affecting partner
- Effect: Fast-acting, local effect
- Procaine cream:
- Advantages: Controllable duration of action
- Note: May affect erection hardness
- Advice: Discuss suitability with doctor
3. 辅助治疗药物 / Adjunctive Treatment Medications
PDE5抑制剂
主要用于勃起功能障碍，但对某些早泄患者也有帮助：
- 西地那非：
- 作用：改善勃起硬度，间接帮助控制射精
- 用法：按需服用
- 注意：需医生处方
- 他达拉非：
- 优点：作用时间较长
- 用法：每日一次或按需服用
PDE5 Inhibitors
Mainly for erectile dysfunction but also help some PE patients:
- Sildenafil:
- Effect: Improves erection hardness, indirectly helps control ejaculation
- Usage: Taken as needed
- Note: Requires doctor’s prescription
- Tadalafil:
- Advantages: Longer duration of action
- Usage: Once daily or as needed
4. 中药与补充剂 / Traditional Chinese Medicine and Supplements
传统中药
需要在中医师指导下使用：
- 锁阳固精丸：温肾固精
- 金匮肾气丸：补肾助阳
- 五子衍宗丸：补肾益精
- 注意：需要辨证施治，不宜自行用药
Traditional Chinese Medicine
Should be used under TCM practitioner’s guidance:
- Suoyang Gujing Wan: Warms kidneys and secures essence
- Jinkui Shenqi Wan: Tonifies kidneys and supports yang
- Wuzi Yanzong Wan: Tonifies kidneys and benefits essence
- Note: Requires syndrome differentiation, not suitable for self-medication
膳食补充剂
证据有限，需谨慎使用：
- 锌补充剂：可能改善性功能
- L-精氨酸：帮助血管扩张
- 人参提取物：传统壮阳药材
- 注意：选择正规品牌，注意剂量
Dietary Supplements
Limited evidence, use with caution:
- Zinc supplements: May improve sexual function
- L-arginine: Helps vasodilation
- Ginseng extract: Traditional aphrodisiac
- Note: Choose reputable brands, pay attention to dosage
5. 用药注意事项 / Medication Precautions
就医咨询重要性
- 必须经过专业诊断后再用药
- 不同病因需要不同药物治疗
- 有些药物需要处方才能购买
- 自行用药可能延误治疗
Importance of Medical Consultation
- Must be professionally diagnosed before medication
- Different causes require different medications
- Some medications require prescriptions
- Self-medication may delay treatment
药物副作用管理
- SSRIs常见副作用：
- 恶心、头痛、失眠
- 性欲减退、射精困难
- 通常随时间减轻
- 局部麻醉剂副作用：
- 局部灼热感
- 可能影响勃起质量
- 伴侣可能被麻醉
Managing Side Effects
- Common SSRI side effects:
- Nausea, headache, insomnia
- Decreased libido, difficult ejaculation
- Usually diminish over time
- Topical anesthetic side effects:
- Local burning sensation
- May affect erection quality
- Partner may be anesthetized
6. 综合治疗建议 / Comprehensive Treatment Advice
药物与非药物结合
- 药物治疗配合行为训练效果更好
- 心理治疗解决根本问题
- 伴侣参与提高治疗效果
- 定期复查调整用药方案
Combining Medication and Non-drug Therapies
- Medication combined with behavioral training works better
- Psychotherapy addresses root causes
- Partner participation improves treatment效果
- Regular follow-up to adjust medication plans
结语 / Conclusion
药物治疗是早泄的有效解决方法，但必须在医生指导下进行。选择合适的药物需要综合考虑病因、身体状况和个人需求。建议及时就医，获得个性化治疗方案。
Medication is an effective solution for PE but must be used under doctor’s guidance. Choosing suitable drugs requires comprehensive consideration of etiology, physical condition and individual needs. Timely medical consultation for personalized treatment plans is recommended.
